N-Light™ rapid tests are powered by the ultra-sensitive AquaSpark™ platform technology and pioneering phage science.
NEMIS is proud to present AquaSpark™, an innovative platform technology that transforms the detection of live bacteria through chemiluminescence. This technology is based on synthetic molecules specifically engineered to emit light when interacting with bacterial enzymes. Our exclusive global rights, secured through a licensing agreement with Ramot at Tel Aviv University, include three pending patents that set us apart in the field of microbiology.
The chemiluminescent light produced by AquaSpark™ is 1000 times brighter than traditional molecules. Consequently, this makes our N-Light™ solution a cutting-edge technology for sensitive detection across a wide range of applications. Due to the virtually endless possibilities of the AquaSpark™ modular toolbox, the N-Light™ platform can be tailored to detect any chosen microorganism, such as bacteria, parasites, viruses, or fungi.
NEMIS has developed unique bacteria-specific enrichment broths containing cocktails of bacteriophages to selectively eliminate competing microflora. NEMIS evaluated and uses 16 individual phages to selectively suppress competing microflora and false-positive bacteria, allowing precise detection of target bacteria without interference. This makes our tests more accurate and specific than rapid tests from competitors. In other words, this unique enrichment broth enhances the growth of targeted pathogens in a single enrichment step. As a result, NEMIS was able to achieve increased specificity and sensitivity of N-Light™ rapid tests.
In addition to leveraging phages for selectivity, NEMIS, in collaboration with ETH, developed an innovative genetically modified reporter phage designed to work with AquaSpark™ for rapid and precise pathogen detection.
NEMIS has created specialized formulations of small assay tablets (3 mm in diameter) that effectively protect AquaSpark™ from environmental factors, significantly increasing the shelf life of the tests. These N-Light™ tablets also contain precise amounts of lysis agents where needed and disintegrate in under 10 seconds—compared to over 10 minutes for conventional tablets—delivering a superior user experience and enhancing assay efficiency.
AquaSpark™ lyophilisates and tablets undergo a comprehensive quality control (QC) testing process at NEMIS. This includes physical properties and verifying the uniform distribution of active ingredients within each batch. We utilize advanced technologies, such as ultra-high-performance liquid chromatography (UHPLC), to accurately detect the minute quantities of AquaSpark™ and other active ingredients in individual tablets (less than 0.05 milligrams).
We operate a cutting-edge biosafety lab for R&D in Au, Switzerland, where we excel in quickly developing robust assay formats.
Our ongoing field studies and pilot trials with clients help refine our offerings and provide tailored solutions, particularly in food safety environments.
Check our field studiesOur expertise in microbial food safety is unmatched, enabling us to promptly address and resolve customer inquiries. This responsiveness not only enhances our brand but also drives customer satisfaction and loyalty, reinforcing NEMIS’s position as a leader in the microbial detection industry.